Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

The transcription factor interferon regulatory factor 5 (IRF5) plays essential roles in pathogen-induced immunity downstream of Toll-, nucleotide-binding oligomerization domain–, and retinoic acid–inducible gene I–like receptors and is an autoimmune susceptibility gene. Normally, inactive in the cyt...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Adv
Κύριοι συγγραφείς: Banga, Jaspreet, Srinivasan, Dinesh, Sun, Chia-Chi, Thompson, Cherrie D., Milletti, Francesca, Huang, Kuo-Sen, Hamilton, Shannon, Song, Su, Hoffman, Ann F., Qin, Yajuan Gu, Matta, Bharati, LaPan, Margaret, Guo, Qin, Lu, Gang, Li, Dan, Qian, Hong, Bolin, David R., Liang, Lena, Wartchow, Charles, Qiu, Jin, Downing, Michelle, Narula, Satwant, Fotouhi, Nader, DeMartino, Julie A., Tan, Seng-Lai, Chen, Gang, Barnes, Betsy J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Association for the Advancement of Science 2020
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228753/
https://ncbi.nlm.nih.gov/pubmed/32440537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay1057
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