טוען...
IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE
Genetic variants within or near the interferon regulatory factor 5 (IRF5) locus associate with systemic lupus erythematosus (SLE) across ancestral groups. The major IRF5-SLE risk haplotype is common across populations, yet immune functions for the risk haplotype are undefined. We characterized the g...
שמור ב:
| הוצא לאור ב: | JCI Insight |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7098722/ https://ncbi.nlm.nih.gov/pubmed/31877114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124020 |
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