Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking

Vulnerability to relapse during periods of attempted abstinence from cocaine use is hypothesized to result from the rewiring of brain reward circuitries, particularly ventral tegmental area (VTA) dopamine neurons. How cocaine exposures act on midbrain dopamine neurons to precipitate addiction-releva...

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Publicat a:Science
Autors principals: Lepack, Ashley E., Werner, Craig T., Stewart, Andrew F., Fulton, Sasha L., Zhong, Ping, Farrelly, Lorna A., Smith, Alexander C. W., Ramakrishnan, Aarthi, Lyu, Yang, Bastle, Ryan M., Martin, Jennifer A., Mitra, Swarup, O’Connor, Richard M., Wang, Zi-Jun, Molina, Henrik, Turecki, Gustavo, Shen, Li, Yan, Zhen, Calipari, Erin S., Dietz, David M., Kenny, Paul J., Maze, Ian
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228137/
https://ncbi.nlm.nih.gov/pubmed/32273471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw8806
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