Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking

Vulnerability to relapse during periods of attempted abstinence from cocaine use is hypothesized to result from the rewiring of brain reward circuitries, particularly ventral tegmental area (VTA) dopamine neurons. How cocaine exposures act on midbrain dopamine neurons to precipitate addiction-releva...

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Publicado no:Science
Main Authors: Lepack, Ashley E., Werner, Craig T., Stewart, Andrew F., Fulton, Sasha L., Zhong, Ping, Farrelly, Lorna A., Smith, Alexander C. W., Ramakrishnan, Aarthi, Lyu, Yang, Bastle, Ryan M., Martin, Jennifer A., Mitra, Swarup, O’Connor, Richard M., Wang, Zi-Jun, Molina, Henrik, Turecki, Gustavo, Shen, Li, Yan, Zhen, Calipari, Erin S., Dietz, David M., Kenny, Paul J., Maze, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228137/
https://ncbi.nlm.nih.gov/pubmed/32273471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw8806
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