Overexpression of BDNF in the ventral tegmental area enhances binge cocaine self-administration in rats exposed to repeated social defeat

Stress is a major risk factor for substance abuse. Intermittent social defeat stress increases drug self-administration (SA) and elevates brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area (VTA) in rats. Intra-VTA BDNF overexpression enhances social defeat stress-induc...

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Gepubliceerd in:Neuropharmacology
Hoofdauteurs: Wang, Junshi, Bastle, Ryan M., Bass, Caroline E., Hammer, Ronald P., Neisewander, Janet L., Nikulina, Ella M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970900/
https://ncbi.nlm.nih.gov/pubmed/27154426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.04.045
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