Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis

Neutrophil extracellular traps (NETs) are formed by polymorphonuclear neutrophils (PMN) and contribute to the innate host defense by binding and killing bacterial and fungal pathogens. Because NET formation depends on histone hypercitrullination by peptidylarginine deiminase 4 (PAD4), we used PAD4 g...

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Publicado no:Immunobiology
Main Authors: Alflen, Astrid, Lopez, Pamela Aranda, Hartmann, Ann-Kathrin, Maxeiner, Joachim, Bosmann, Markus, Sharma, Arjun, Platten, Johannes, Ries, Frederic, Beckert, Hendrik, Ruf, Wolfram, Radsak, Markus P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227411/
https://ncbi.nlm.nih.gov/pubmed/31761474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2019.11.002
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