Intrapulmonary, Adenovirus-Mediated Overexpression of KARAP/DAP12 Enhances Fungal Clearance during Invasive Aspergillosis

Herein, we report that the intrapulmonary delivery of an adenovirus vector expressing KARAP/DAP12, an adaptor protein expressed in granulocytes and mononuclear cells, enhanced fungal clearance during experimental invasive pulmonary aspergillosis in neutropenic mice.

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Detalhes bibliográficos
Main Authors: Carpenter, Kristin J., Buckland, Karen F., Xing, Zhou, Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307040/
https://ncbi.nlm.nih.gov/pubmed/16299339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8402-8406.2005
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