Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis

Neutrophil extracellular traps (NETs) are formed by polymorphonuclear neutrophils (PMN) and contribute to the innate host defense by binding and killing bacterial and fungal pathogens. Because NET formation depends on histone hypercitrullination by peptidylarginine deiminase 4 (PAD4), we used PAD4 g...

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Publicado en:Immunobiology
Autores principales: Alflen, Astrid, Lopez, Pamela Aranda, Hartmann, Ann-Kathrin, Maxeiner, Joachim, Bosmann, Markus, Sharma, Arjun, Platten, Johannes, Ries, Frederic, Beckert, Hendrik, Ruf, Wolfram, Radsak, Markus P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227411/
https://ncbi.nlm.nih.gov/pubmed/31761474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2019.11.002
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