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Upregulation of pERK and c-JUN by γ-tocotrienol and not α-tocopherol are essential to the differential effect on apoptosis in prostate cancer cells

BACKGROUND: α-tocopherol (AT) and γ-tocotrienol (GT3) are vitamin E isoforms considered to have potential chemopreventive properties. AT has been widely studied in vitro and in clinical trials with mixed results. The latest clinical study (SELECT trial) tested AT in prostate cancer patients, determi...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Moore, Christine, Palau, Victoria E., Mahboob, Rashid, Lightner, Janet, Stone, William, Krishnan, Koyamangalath
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227069/
https://ncbi.nlm.nih.gov/pubmed/32414345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06947-6
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