Upregulation of pERK and c-JUN by γ-tocotrienol and not α-tocopherol are essential to the differential effect on apoptosis in prostate cancer cells

BACKGROUND: α-tocopherol (AT) and γ-tocotrienol (GT3) are vitamin E isoforms considered to have potential chemopreventive properties. AT has been widely studied in vitro and in clinical trials with mixed results. The latest clinical study (SELECT trial) tested AT in prostate cancer patients, determi...

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Zapisane w:
Opis bibliograficzny
Wydane w:BMC Cancer
Główni autorzy: Moore, Christine, Palau, Victoria E., Mahboob, Rashid, Lightner, Janet, Stone, William, Krishnan, Koyamangalath
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2020
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227069/
https://ncbi.nlm.nih.gov/pubmed/32414345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06947-6
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