Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia

Background: Bronchopulmonary dysplasia (BPD) is a lung disease of preterm born infants, characterized by alveolar simplification. MicroRNA (miR) are known to be involved in many biological and pathological processes in the lung. Although a changed expression has been described for several miR in BPD...

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Published in:Cells
Main Authors: Chao, Cho-Ming, Carraro, Gianni, Rako, Zvonimir A., Kolck, Johannes, Sedighi, Jamschid, Zimmermann, Volker, Moiseenko, Alena, Wilhelm, Jochen, Young, Brittany M., Chong, Lei, Wu, Jin, Contreras, Adriana, Minoo, Parviz, Barreto, Guillermo, Warburton, David, Bellusci, Saverio
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226730/
https://ncbi.nlm.nih.gov/pubmed/32252341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040859
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