WNT5a-ROR Signaling Is Essential for Alveologenesis

WNT5a is a mainly “non-canonical” WNT ligand whose dysregulation is observed in lung diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and asthma. Germline deletion of Wnt5a disrupts embryonic lung development. However, the temporal-specific function...

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Udgivet i:Cells
Main Authors: Li, Changgong, Smith, Susan M, Peinado, Neil, Gao, Feng, Li, Wei, Lee, Matt K, Zhou, Beiyun, Bellusci, Saverio, Pryhuber, Gloria S, Ho, Hsin-Yi Henry, Borok, Zea, Minoo, Parviz
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072327/
https://ncbi.nlm.nih.gov/pubmed/32046118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020384
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