FGF10 (Fibroblast Growth Factor 10) plays a causative role in the tracheal cartilage defects in a mouse model of Apert Syndrome

Patients with Apert Syndrome (AS) display a wide range of congenital malformations including tracheal stenosis, which is a disease characterized by a uniform cartilaginous sleeve in place of a normally ribbed cartilagenous trachea. We have studied the cellular and molecular basis of this phenotype i...

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Autori principali: Tiozzo, Caterina, De Langhe, Stjin, Carraro, Gianni, Al Alam, Denise, Nagy, Andre, Wigfall, Clarence, Hajihosseini, Mohammad K., Warburton, David, Minoo, Parviz, Bellusci, Saverio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725279/
https://ncbi.nlm.nih.gov/pubmed/19581825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181b45580
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