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The Inhibition of Wnt Restrain KRAS(G12V)-Driven Metastasis in Non-Small-Cell Lung Cancer
The KRAS mutations have been an obstacle to identify therapeutic targets in cancer treatment. In this work, we clarified the distinct metastasis pattern of non-small-cell lung carcinoma (NSCLC) induced by KRAS(G12V)/KRAS(G12D) mutations and inhibited the KRAS(G12V) mediated metastasis by Wnt inhibit...
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| Publié dans: | Cancers (Basel) |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226522/ https://ncbi.nlm.nih.gov/pubmed/32244355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040837 |
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