The Status of p53 Oligomeric and Aggregation States in Cancer

Despite being referred to as the guardian of the genome, when impacted by mutations, p53 can lose its protective functions and become a renegade. The malignant transformation of p53 occurs on multiple levels, such as altered DNA binding properties, acquisition of novel cellular partners, or associat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: de Oliveira, Guilherme A. P., Petronilho, Elaine C., Pedrote, Murilo M., Marques, Mayra A., Vieira, Tuane C. R. G., Cino, Elio A., Silva, Jerson L.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226498/
https://ncbi.nlm.nih.gov/pubmed/32260447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040548
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