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Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation

Background: The recently developed antiandrogen, Enzalutamide (Enz), has reformed the standard of care for castration resistant prostate cancer (CRPC) patients. However, Enz-resistance inevitably emerges despite success of Enz in prolonging CRPC patients’ survival. Here we found that Enz-resistant p...

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Xu, Hua, Sun, Yin, Huang, Chi-Ping, You, Bosen, Ye, Dingwei, Chang, Chawnshang
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226306/
https://ncbi.nlm.nih.gov/pubmed/32235588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040831
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