Antiproliferative and Antimigration Activities of Fluoro-Neplanocin A via Inhibition of Histone H3 Methylation in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is among the most aggressive and potentially metastatic malignancies. Most affected patients have poor clinical outcomes due to the lack of specific molecular targets on tumor cells. The upregulated expression of disruptor of telomeric silencing 1-like (DOT1L), a...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Byun, Woong Sub, Kim, Won Kyung, Yoon, Ji-seong, Jarhad, Dnyandev B., Jeong, Lak Shin, Lee, Sang Kook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226301/
https://ncbi.nlm.nih.gov/pubmed/32244385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040530
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