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Inhibition of DOT1L by Half-Selenopsammaplin A Analogs Suppresses Tumor Growth and EMT-Mediated Metastasis in Triple-Negative Breast Cancer

Due to a lack of hormone receptors, current treatment strategies for triple-negative breast cancer (TNBC) are limited with frequent disease recurrence and metastasis. Recent findings have suggested that aberrant methylation of histone H3 lysine 79 residue (H3K79me) by the histone methyltransferase d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmaceuticals (Basel)
Egile Nagusiak: Byun, Woong Sub, Lee, Gyu Ho, Park, Hyeung-geun, Lee, Sang Kook
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824081/
https://ncbi.nlm.nih.gov/pubmed/33379275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010018
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