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Targeting the Acidic Tumor Microenvironment: Unexpected Pro-Neoplastic Effects of Oral NaHCO(3) Therapy in Murine Breast Tissue

The acidic tumor microenvironment modifies malignant cell behavior. Here, we study consequences of the microenvironment in breast carcinomas. Beginning at carcinogen-based breast cancer induction, we supply either regular or NaHCO(3)-containing drinking water to female C57BL/6j mice. We evaluate uri...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Voss, Ninna C. S., Dreyer, Thomas, Henningsen, Mikkel B., Vahl, Pernille, Honoré, Bent, Boedtkjer, Ebbe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226235/
https://ncbi.nlm.nih.gov/pubmed/32268614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040891
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