Targeting the Acidic Tumor Microenvironment: Unexpected Pro-Neoplastic Effects of Oral NaHCO(3) Therapy in Murine Breast Tissue

The acidic tumor microenvironment modifies malignant cell behavior. Here, we study consequences of the microenvironment in breast carcinomas. Beginning at carcinogen-based breast cancer induction, we supply either regular or NaHCO(3)-containing drinking water to female C57BL/6j mice. We evaluate uri...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Voss, Ninna C. S., Dreyer, Thomas, Henningsen, Mikkel B., Vahl, Pernille, Honoré, Bent, Boedtkjer, Ebbe
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226235/
https://ncbi.nlm.nih.gov/pubmed/32268614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040891
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