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NaHCO(3) dilates mouse afferent arteriole via Na(+)/HCO(3) cotransporters NBCs

Sodium bicarbonate has long been used to treat chronic kidney disease (CKD). It has been demonstrated to slow the decline in glomerular filtration rate (GFR) in CKD patient; however, the mechanisms are not completely understood. We hypothesized that NaHCO(3) dilates afferent arterioles (Af-Art) by s...

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Bibliographische Detailangaben
Veröffentlicht in:Hypertension
Hauptverfasser: Jiang, Shan, Wang, Ximing, Wei, Jin, Zhang, Gensheng, Zhang, Jie, Xie, Peng, Xu, Lan, Wang, Lei, Zhao, Liang, Li, Lingli, Wilcox, Christopher S., Chen, Jianghua, Lai, En Yin, Liu, Ruisheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785401/
https://ncbi.nlm.nih.gov/pubmed/31522618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13235
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