SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications

Stemness in sarcomas is coordinated by the expression of pluripotency factors, like SOX2, in cancer stem cells (CSC). The role of SOX2 in tumor initiation and progression has been well characterized in osteosarcoma. However, the pro-tumorigenic features of SOX2 have been scarcely investigated in oth...

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Udgivet i:Cancers (Basel)
Main Authors: Menendez, Sofia T., Rey, Veronica, Martinez-Cruzado, Lucia, Gonzalez, M. Victoria, Morales-Molina, Alvaro, Santos, Laura, Blanco, Verónica, Alvarez, Carlos, Estupiñan, Oscar, Allonca, Eva, Rodrigo, Juan Pablo, García-Castro, Javier, Garcia-Pedrero, Juana Maria, Rodriguez, Rene
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226033/
https://ncbi.nlm.nih.gov/pubmed/32295077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040964
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