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SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications

Stemness in sarcomas is coordinated by the expression of pluripotency factors, like SOX2, in cancer stem cells (CSC). The role of SOX2 in tumor initiation and progression has been well characterized in osteosarcoma. However, the pro-tumorigenic features of SOX2 have been scarcely investigated in oth...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Menendez, Sofia T., Rey, Veronica, Martinez-Cruzado, Lucia, Gonzalez, M. Victoria, Morales-Molina, Alvaro, Santos, Laura, Blanco, Verónica, Alvarez, Carlos, Estupiñan, Oscar, Allonca, Eva, Rodrigo, Juan Pablo, García-Castro, Javier, Garcia-Pedrero, Juana Maria, Rodriguez, Rene
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226033/
https://ncbi.nlm.nih.gov/pubmed/32295077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040964
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