FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway()

Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene FUS-CHOP, SRC have been found as one of the most activated kinases. Here we used a...

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Vydáno v:Neoplasia
Hlavní autoři: Tornin, Juan, Hermida-Prado, Francisco, Padda, Ranjit Singh, Gonzalez, M. Victoria, Alvarez-Fernandez, Carlos, Rey, Veronica, Martinez-Cruzado, Lucia, Estupiñan, Oscar, Menendez, Sofia T., Fernandez-Nevado, Lucia, Astudillo, Aurora, Rodrigo, Juan P., Lucien, Fabrice, Kim, Yohan, Leong, Hon S., Garcia-Pedrero, Juana Maria, Rodriguez, Rene
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2017
Témata:
Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747526/
https://ncbi.nlm.nih.gov/pubmed/29190494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.11.004
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