FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway()

Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene FUS-CHOP, SRC have been found as one of the most activated kinases. Here we used a...

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Pubblicato in:Neoplasia
Autori principali: Tornin, Juan, Hermida-Prado, Francisco, Padda, Ranjit Singh, Gonzalez, M. Victoria, Alvarez-Fernandez, Carlos, Rey, Veronica, Martinez-Cruzado, Lucia, Estupiñan, Oscar, Menendez, Sofia T., Fernandez-Nevado, Lucia, Astudillo, Aurora, Rodrigo, Juan P., Lucien, Fabrice, Kim, Yohan, Leong, Hon S., Garcia-Pedrero, Juana Maria, Rodriguez, Rene
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2017
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747526/
https://ncbi.nlm.nih.gov/pubmed/29190494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.11.004
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