Llwytho...

Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells

Myeloid cell leukemia 1 (Mcl-1) and B-cell lymphoma 2 (Bcl-2) proteins are promising targets for cancer therapy. Here, we investigated the structure–activity relationships (SARs) and performed molecular docking analysis of renieramycin T (RT) and its analogues and identified the critical functional...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Petsri, Korrakod, Yokoya, Masashi, Tungsukruthai, Sucharat, Rungrotmongkol, Thanyada, Nutho, Bodee, Vinayanuwattikun, Chanida, Saito, Naoki, Takehiro, Matsubara, Sato, Ryo, Chanvorachote, Pithi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226000/
https://ncbi.nlm.nih.gov/pubmed/32260280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040875
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