Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells

Myeloid cell leukemia 1 (Mcl-1) and B-cell lymphoma 2 (Bcl-2) proteins are promising targets for cancer therapy. Here, we investigated the structure–activity relationships (SARs) and performed molecular docking analysis of renieramycin T (RT) and its analogues and identified the critical functional...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Korrakod Petsri, Masashi Yokoya, Sucharat Tungsukruthai, Thanyada Rungrotmongkol, Bodee Nutho, Chanida Vinayanuwattikun, Naoki Saito, Matsubara Takehiro, Ryo Sato, Pithi Chanvorachote
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2020-04-01
סדרה:Cancers
נושאים:
renieramycin T
Structure–Activity Relationship
patient-derived primary lung cancer cells
lung cancer
apoptosis
Mcl-1
גישה מקוונת:https://www.mdpi.com/2072-6694/12/4/875
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים