Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system

Models for enteric neuropathies, in which intestinal nerves are absent or injured, are required to evaluate possible cell therapies. However, existing options, including transgenic mice, are variable and fragile. Here immunocompromised mice were implanted with human pluripotent stem cell–derived tis...

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Detalles Bibliográficos
Publicado en:J Tissue Eng
Main Authors: Chang, David F, Zuber, Samuel M, Gilliam, Elizabeth A, Nucho, Laura-Marie A, Levin, Gabriel, Wang, Fengnan, Squillaro, Anthony I, Huang, Sha, Spence, Jason R, Grikscheit, Tracy C
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2020
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225796/
https://ncbi.nlm.nih.gov/pubmed/32435442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2041731420905701
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