Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine

Acquired or congenital disruption in enteric nervous system (ENS) development or function can lead to significant mechanical dysmotility. ENS restoration through cellular transplantation may provide a cure for enteric neuropathies. We have previously generated human pluripotent stem cell (hPSC)-deri...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Schlieve, Christopher R., Fowler, Kathryn L., Thornton, Matthew, Huang, Sha, Hajjali, Ibrahim, Hou, Xiaogang, Grubbs, Brendan, Spence, Jason R., Grikscheit, Tracy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599241/
https://ncbi.nlm.nih.gov/pubmed/28803915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.07.017
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