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Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche

BACKGROUND & AIMS: For patients with short-bowel syndrome, intestinal adaptation is required to achieve enteral independence. Although adaptation has been studied extensively in animal models, little is known about this process in human intestine. We hypothesized that analysis of matched specime...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Wieck, Minna M., Schlieve, Christopher R., Thornton, Matthew E., Fowler, Kathryn L., Isani, Mubina, Grant, Christa N., Hilton, Ashley E., Hou, Xiaogang, Grubbs, Brendan H., Frey, Mark R., Grikscheit, Tracy C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403975/
https://ncbi.nlm.nih.gov/pubmed/28462379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.12.008
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