Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche

BACKGROUND & AIMS: For patients with short-bowel syndrome, intestinal adaptation is required to achieve enteral independence. Although adaptation has been studied extensively in animal models, little is known about this process in human intestine. We hypothesized that analysis of matched specime...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Wieck, Minna M., Schlieve, Christopher R., Thornton, Matthew E., Fowler, Kathryn L., Isani, Mubina, Grant, Christa N., Hilton, Ashley E., Hou, Xiaogang, Grubbs, Brendan H., Frey, Mark R., Grikscheit, Tracy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403975/
https://ncbi.nlm.nih.gov/pubmed/28462379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.12.008
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