Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche

BACKGROUND & AIMS: For patients with short-bowel syndrome, intestinal adaptation is required to achieve enteral independence. Although adaptation has been studied extensively in animal models, little is known about this process in human intestine. We hypothesized that analysis of matched specime...

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發表在:Cell Mol Gastroenterol Hepatol
Main Authors: Wieck, Minna M., Schlieve, Christopher R., Thornton, Matthew E., Fowler, Kathryn L., Isani, Mubina, Grant, Christa N., Hilton, Ashley E., Hou, Xiaogang, Grubbs, Brendan H., Frey, Mark R., Grikscheit, Tracy C.
格式: Artigo
語言:Inglês
出版: Elsevier 2017
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Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403975/
https://ncbi.nlm.nih.gov/pubmed/28462379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.12.008
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