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Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system

Models for enteric neuropathies, in which intestinal nerves are absent or injured, are required to evaluate possible cell therapies. However, existing options, including transgenic mice, are variable and fragile. Here immunocompromised mice were implanted with human pluripotent stem cell–derived tis...

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Detalhes bibliográficos
Publicado no:J Tissue Eng
Main Authors: Chang, David F, Zuber, Samuel M, Gilliam, Elizabeth A, Nucho, Laura-Marie A, Levin, Gabriel, Wang, Fengnan, Squillaro, Anthony I, Huang, Sha, Spence, Jason R, Grikscheit, Tracy C
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225796/
https://ncbi.nlm.nih.gov/pubmed/32435442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2041731420905701
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