Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells

Whereas hundreds of cells in the mouse embryonic aorta transdifferentiate to hematopoietic cells, only very few establish hematopoietic stem cell (HSC) identity at a single time point. The Gata2 transcription factor is essential for HSC generation and function. In contrast to surface-marker-based ce...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Vink, Chris Sebastiaan, Calero-Nieto, Fernando Jose, Wang, Xiaonan, Maglitto, Antonio, Mariani, Samanta Antonella, Jawaid, Wajid, Göttgens, Berthold, Dzierzak, Elaine
Format: Artigo
Langue:Inglês
Publié: Cell Press 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225750/
https://ncbi.nlm.nih.gov/pubmed/32402290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107627
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires