Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells

Whereas hundreds of cells in the mouse embryonic aorta transdifferentiate to hematopoietic cells, only very few establish hematopoietic stem cell (HSC) identity at a single time point. The Gata2 transcription factor is essential for HSC generation and function. In contrast to surface-marker-based ce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Vink, Chris Sebastiaan, Calero-Nieto, Fernando Jose, Wang, Xiaonan, Maglitto, Antonio, Mariani, Samanta Antonella, Jawaid, Wajid, Göttgens, Berthold, Dzierzak, Elaine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225750/
https://ncbi.nlm.nih.gov/pubmed/32402290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107627
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