Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are generated from specialized endothelial cells of the embryonic aorta. Inflammatory factors are implicated in regulating mouse HSC development, but which cells in the aorta-gonad-mesonephros (AGM) microenvironment produce these factors is unknown. In the adult, macr...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Mariani, Samanta Antonella, Li, Zhuan, Rice, Siobhan, Krieg, Carsten, Fragkogianni, Stamatina, Robinson, Mark, Vink, Chris Sebastiaan, Pollard, Jeffrey William, Dzierzak, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591003/
https://ncbi.nlm.nih.gov/pubmed/31178352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.05.003
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