Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are generated from specialized endothelial cells of the embryonic aorta. Inflammatory factors are implicated in regulating mouse HSC development, but which cells in the aorta-gonad-mesonephros (AGM) microenvironment produce these factors is unknown. In the adult, macr...

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Опубликовано в: :Immunity
Главные авторы: Mariani, Samanta Antonella, Li, Zhuan, Rice, Siobhan, Krieg, Carsten, Fragkogianni, Stamatina, Robinson, Mark, Vink, Chris Sebastiaan, Pollard, Jeffrey William, Dzierzak, Elaine
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591003/
https://ncbi.nlm.nih.gov/pubmed/31178352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.05.003
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