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Genome Editing Fidelity in the Context of DNA Sequence and Chromatin Structure

Genome editing by Clustered Regularly Inter Spaced Palindromic Repeat (CRISPR) associated (Cas) systems has revolutionized medical research and holds enormous promise for correcting genetic diseases. Understanding how these Cas nucleases work and induce mutations, as well as identifying factors that...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Chechik, Lyuba, Martin, Ophelie, Soutoglou, Evi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225291/
https://ncbi.nlm.nih.gov/pubmed/32457906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00319
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