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An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy

PURPOSE: Clearance via renal replacement therapy (RRT) can significantly alter the pharmacokinetic profile of drugs. The aim of this study was (i) to improve the use of clinical trial data and (ii) to provide a model that allows quantification of all aspects of drug elimination via RRT including ads...

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Опубликовано в: :Pharm Res
Главные авторы: Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A., Wicha, Sebastian G.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225193/
https://ncbi.nlm.nih.gov/pubmed/32409892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02832-w
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