An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy

PURPOSE: Clearance via renal replacement therapy (RRT) can significantly alter the pharmacokinetic profile of drugs. The aim of this study was (i) to improve the use of clinical trial data and (ii) to provide a model that allows quantification of all aspects of drug elimination via RRT including ads...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A., Wicha, Sebastian G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225193/
https://ncbi.nlm.nih.gov/pubmed/32409892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-020-02832-w
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