Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

Viral escape from CD8(+) cytotoxic T lymphocyte responses correlates with disease progression and represents a significant challenge for vaccination. Here, we demonstrate that CD8(+) T cell recognition of the naturally occurring MHC-I-restricted LCMV-associated immune escape variant Y4F is restored...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Duru, Adil Doganay, Sun, Renhua, Allerbring, Eva B., Chadderton, Jesseka, Kadri, Nadir, Han, Xiao, Peqini, Kaliroi, Uchtenhagen, Hannes, Madhurantakam, Chaithanya, Pellegrino, Sara, Sandalova, Tatyana, Nygren, Per-Åke, Turner, Stephen J., Achour, Adnane
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224568/
https://ncbi.nlm.nih.gov/pubmed/32365082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008244
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