Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8

7C8 is a mouse monoclonal antibody that is specific for the third hypervariable loop (V3 loop) of the human immunodeficiency virus type 2 (HIV-2) associated protein gp125. Fab fragments of 7C8 effectively neutralize HIV-2. 7C8 was expressed and purified from a hybridoma cell line in order to establi...

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Bibliographische Detailangaben
Hauptverfasser: Uchtenhagen, Hannes, Sourial, Samer, Friemann, Rosmarie, Ehnlund, Mariethe, Spetz, Anna-Lena, Harris, Robert A., Madhurantakam, Chaithanya, Achour, Adnane
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2009
Schlagworte:
Crystallization Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705640/
https://ncbi.nlm.nih.gov/pubmed/19574645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109020685
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