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MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways

Apoptosis is a genetically programmed cell death process with profound roles in development and disease. MicroRNAs modulate the expression of many proteins and are often deregulated in human diseases, such as cancer. C. elegans germ cells undergo apoptosis in response to genotoxic stress by the comb...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Tran, Anh T., Chapman, Eric M., Flamand, Mathieu N., Yu, Bin, Krempel, Samuel J., Duchaine, Thomas F., Eroglu, Matthew, Derry, W. Brent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224216/
https://ncbi.nlm.nih.gov/pubmed/30952991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0325-6
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