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Run-on of germline apoptosis promotes gonad senescence in C. elegans

Aging (senescence) includes causal mechanisms (etiologies) of late-life disease, which remain poorly understood. According to the recently proposed hyperfunction theory, based on the older theory of antagonistic pleiotropy, senescent pathologies can arise from futile, post-reproductive run-on of pro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: de la Guardia, Yila, Gilliat, Ann F., Hellberg, Josephine, Rennert, Peter, Cabreiro, Filipe, Gems, David
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129915/
https://ncbi.nlm.nih.gov/pubmed/27256978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9681
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