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Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury
Hypoxic injury results in cell death, tissue damage and activation of inflammatory pathways. This is mediated by pathological Connexin43 (Cx43) hemichannel (HC) opening resulting in osmotic and ionic imbalances as well as cytokine production perpetuating the inflammatory environment. Gap19 is an int...
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| Publicado no: | Drug Deliv Transl Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7223318/ https://ncbi.nlm.nih.gov/pubmed/32318976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-020-00763-y |
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