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Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells

Transplantation of umbilical cord mesenchymal stem cells (UC-MSCs) is currently considered a novel therapeutic strategy for diabetic nephropathy (DN). However, the mechanisms by which UC-MSCs ameliorate renal fibrosis in DN are not well understood. Herein, we firstly investigated the therapeutic eff...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Diabetes Res
Κύριοι συγγραφείς: Li, Hongde, Rong, Pengfei, Ma, Xiaoqian, Nie, Wei, Chen, Yan, Zhang, Juan, Dong, Qiong, Yang, Min, Wang, Wei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Hindawi 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222483/
https://ncbi.nlm.nih.gov/pubmed/32455132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3847171
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