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Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells

Transplantation of umbilical cord mesenchymal stem cells (UC-MSCs) is currently considered a novel therapeutic strategy for diabetic nephropathy (DN). However, the mechanisms by which UC-MSCs ameliorate renal fibrosis in DN are not well understood. Herein, we firstly investigated the therapeutic eff...

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Bibliografiske detaljer
Udgivet i:J Diabetes Res
Main Authors: Li, Hongde, Rong, Pengfei, Ma, Xiaoqian, Nie, Wei, Chen, Yan, Zhang, Juan, Dong, Qiong, Yang, Min, Wang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7222483/
https://ncbi.nlm.nih.gov/pubmed/32455132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3847171
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