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N-Acetylation of Amines in Continuous-Flow with Acetonitrile—No Need for Hazardous and Toxic Carboxylic Acid Derivatives

A continuous-flow acetylation reaction was developed, applying cheap and safe reagent, acetonitrile as acetylation agent and alumina as catalyst. The method developed utilizes milder reagent than those used conventionally. The reaction was tested on various aromatic and aliphatic amines with good co...

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Vydáno v:Molecules
Hlavní autoři: Orsy, György, Fülöp, Ferenc, Mándity, István M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221708/
https://ncbi.nlm.nih.gov/pubmed/32340371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25081985
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