Continuous-Flow Synthesis of Thioureas, Enabled by Aqueous Polysulfide Solution

We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditions. The crystallized products were isolated by si...

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Bibliographic Details
Published in:Molecules
Main Authors: Németh, András Gy., Szabó, Renáta, Orsy, György, Mándity, István M., Keserű, György M., Ábrányi-Balogh, Péter
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827778/
https://ncbi.nlm.nih.gov/pubmed/33435580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020303
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