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Continuous-Flow Synthesis of Thioureas, Enabled by Aqueous Polysulfide Solution

We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditions. The crystallized products were isolated by si...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Németh, András Gy., Szabó, Renáta, Orsy, György, Mándity, István M., Keserű, György M., Ábrányi-Balogh, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827778/
https://ncbi.nlm.nih.gov/pubmed/33435580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020303
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