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Continuous-flow retro-Diels–Alder reaction: an efficient method for the preparation of pyrimidinone derivatives

The syntheses of various pyrimidinones as potentially bioactive products by means of the highly controlled continuous-flow retro-Diels–Alder reaction of condensed pyrimidinone derivatives are presented. Noteworthy, the use of this approach allowed us to rapidly screen a selection of conditions and q...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Nekkaa, Imane, Palkó, Márta, Mándity, István M, Fülöp, Ferenc
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815275/
https://ncbi.nlm.nih.gov/pubmed/29507637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.20
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