Single-Cell Analysis Reveals Partial Reactivation of X Chromosome instead of Chromosome-wide Dampening in Naive Human Pluripotent Stem Cells

Recently, a unique form of X chromosome dosage compensation has been demonstrated in human preimplantation embryos, which happens through the dampening of X-linked gene expression from both X chromosomes. Subsequently, X chromosome dampening has also been demonstrated in female human pluripotent ste...

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Pubblicato in:Stem Cell Reports
Autori principali: Mandal, Susmita, Chandel, Deepshikha, Kaur, Harman, Majumdar, Sudeshna, Arava, Maniteja, Gayen, Srimonta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221091/
https://ncbi.nlm.nih.gov/pubmed/32359444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.03.027
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